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Ashley Essick

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AshleyEssick Essick







Ashley Essick, MBA, PMP is a Global Project Manager at ICON PLC, a leading global contract research organization, where she leads complex oncology and plasma-derived therapy programs spanning 23 countries across all major global regions. She holds an MBA and the Project Management Professional (PMP) certification, and is currently completing MIT Professional Education's Applied Agentic AI for Organizational Transformation program alongside active pursuit of AI governance certification through the International Association of Privacy Professionals (IAPP).

With 13 years of progressive healthcare operations experience and 7 years leading global Phase I through III clinical trials, Ashley has contributed operationally to three FDA-approved therapies: Inlexzo (TAR-200, first-in-class bladder cancer), Zepbound (tirzepatide, obesity), and the Wegovy cardiovascular indication (semaglutide). Her programs have engaged cross-functional teams spanning clinical operations, regulatory affairs, data management, finance, and global site networks across 23 countries.

Ashley architects AI-forward solutions at the intersection of clinical operations, enterprise governance, and regulated drug development. As Product Owner for ICON's enterprise Operational Resourcing and Forecasting Platform, she led the initiative through full C-suite endorsement and ILT approval, with projected conservative annual operational savings of $16M at full scale. She has designed a broader portfolio of 18 AI solutions mapped across a phased enterprise rollout, which has received full organizational approval, positioning her as a strategic architect of AI adoption at scale. Her work is grounded in direct experience managing complex global programs where AI governance is not a theoretical exercise but an operational necessity. She writes and speaks on practical frameworks that give project teams accountability over AI output, not just access to it. The views expressed are the author’s own.

Profile created May 2026

Articles and Papers

  • AI Accountability Is Already PM Work: Why Project Managers Should Lead the Guardrails Conversation Now - Advisory Article - Essick - May 2026

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